Sligo Rovers exited the EA Sports Cup after a 1-0 defeat against Derry City in The Showgrounds.
Rory Patterson notched the matchwinner for the Candystripes, scoring after the 13th minute.
The experimental Rovers side went close to equalising through Sean Maguire in the second-half but Roddy Collins' side emerged with the victory to reach the quarter-finals.
The Bit o' Red made eight changes from Saturday's 2-2 draw with St Patrick's Athletic in the SSE Airtricity Premier Division.
Gary Boylan was handed his debut while Jake Dykes was also selected in a youthful Rovers defence.
Derry had three corners in the opening minutes as they made the better start to the game.
Rovers first threatened in the seventh minute as Eric Odhiambo's cross fell to Sean Maguire, he put it across goal but Derry goalkeeper Ciaran Gallagher dived down on the ball.
Maguire shot over the bar two minutes later after gaining control of the ball just inside the penalty box.
Derry took the lead on 14 minutes through Patterson.
Tony McNamee found Rory Patterson on the left of the box, he took the ball onto his right foot and finished past Brush via the inside of the far post.
The Bit o' Red had a succession of corner midway through the half and almost equalised when Ryan McBride headed over defenind one of the set-pieces.
Patterson missed a great chance to double City's advantage. It was Tony McNamee again that picked out the striker with a fine cross but the header was over the crossbar.
Danny Ledwith curled a free-kick from 25 yards out just by the post after Maguire had been taken down.
Brush had to make a save from Tony McNamee on 37 as his low, hard shot forced the goalkeeper into a good stop.
Rovers were unchanged at the break, while Derry brought on John Paul McGovern from Barry McNamee.
Former Rovers man Danny Ventre was booked in the 52nd minute for time-wasting, he was substituted shortly afterwards for Raymond Foy with a warm reception from the home supporters.
The open phases on the half was scrappy with no chances for either side. Richard Brush picked up a knocking, forcing the introduction of Gary Rovers just after the hour mark and Paul O'Conor also came on for Danny Ledwith.
Roddy Collins junior's tremendous strike from distance was tipped over by Rogers as he did brilliantly well to deny Derry.
The resulting corner from Dean Jarvis was cleared to McGovern but he couldn't connect well with his effort at goal and it rolled well wide.
Paul O'Conor produced a nice touch to put Kieran Djilali in space on 66 minutes but there was too much on his cross and it was missed by the Rovers players in the middle of the penalty area.
Another corner from Jarvis found the head of Ryan McBride and it was another excellent saved from the outstretched hand of Gary Rogers to push it around the post.
Rovers did go close as Eric Odhiambo's cross to Sean Maguire at the near post saw a good head from the West Ham United loaneed and it was saved by Gallagher.
Regan Donelan was handed his debut for the club with 14 minutes as he came on for Ross Gaynor.
Ian Baraclough's side tried to make a breakthrough in the closing minutes and came close to equalising when Sean Maguire missed a golden opportunity, heading over the bar from the edge of the six yard box from Donelan's cross as Derry held on to progress.
Rovers team: Brush (Rogers 61), Dykes, Boylan, Spillane, Gaynor (Donelan 77), Odhiambo, Conneely, Ledwith (O'Conor 61), Djilali, Maguire, North (c).
Derry team: Gallagher, Collins, Jarvis, Burke, McBride, T McNamee, Ventre (Foy 53), Barry, B McNamee (McGovern 45), Boyle (Timlin 71), Patterson(c).